The first time you use the OXI one or every time you load a new project, each sequencer has by default a Midi channel assigned. Seq 1 is Midi ch 1, seq 2, channel 2 and so on up to channel 4.

By default the sequencers are configured in the following modes:

Sequencer 1 -> MONO
Sequencer 2 -> MONO or POLY
Sequencer 3 -> CHORD
Sequencer 4 -> MULTITRACK

Of course you can change the modes to your needs but I’m going to follow this default sequencer configuration for this explanation.

Open your DAW and create 4 MIDI tracks, each of them should have assigned a different MIDI channel from 1 to 4. If you don’t set the MIDI channels accordingly, they will be set to ALL by default and all the sequencers notes will be mixed up.

In some DAWs like Ableton you also need to turn Monitoring ON on that tracks so the incomming MIDI signals are forwarded to the MIDI instruments we load on these tracks.

ABLETON

BITWIG

On tracks 1 (MIDI Channel 1) and track 2 (MIDI Channel 2) you can load a Mono synth.
On track 3 (MIDI Channel 3) load a Poly synth for the chords.
On track 4 (MIDI Channel 4) add a stock drum kit or any Drums plugin.

Add some steps in every sequencer of the OXI One and press Play.
If everything is properly configured you should hear some sounds coming from the instruments you loaded.

To keep your DAW and your OXI One in Sync, the easiest way is to slave the OXI One to the DAW.
Then, once you press play in your DAW, the OXI One will start playing.
OXI One has to be set to USB Sync otherwise Autoclock must be enabled.

DAW Sync settings

ABLETON
Ableton sync settings

BITWIG